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*KLOTHO gene was discovered in 1997, in mice, to extend the lifespan when overexpressed, while it accelerates aging when its expression is disrupted. The name of this longevity gene comes from the Greek goddess Klotho. In Greek mythology, it was Klotho who controlled the lives and destinies of everyone. The Klotho gene codes for a transmembrane protein, the extra-cellular domain of which is shed and secreted. The secreted Klotho protein inhibits the phosphorylation of the IGF1 receptor which leads to the repression of the insulin / IGF-1 pathway. Therefore, Klotho activity results in an activation of **FOXO. Activation of FOXO will induce anti-aging activity by stimulating detoxification and DNA-repair genes.
***The telomere is a region of non-coding DNA that is located at the ends of chromosomes (X- shaped).
****Glutathione peroxidase (GP) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.
YOUTH EXPERT™ Global Anti-Aging Cream #2 is a rich formulated, luxurious cream dedicated to prestigious skin therapies targeted on global rejuvenation – real results™. Cream is suitable for daily care for skin of all types of age 40~45+. .
GEN’X-17-GAA™ Complex: Orange Stem Cells + Baicalin (Telomere Protector) + Apitoxin (Bee Venom) + Crystal Tears™
Complementary components – typical to the age group
Re-densifying & Lifting: Lipodipeptide Tyrosyl-Arginyl
Anti-wrinkle Filler: 2x Hyaluronic Acid (cross-linked HA + HA 50 kDa)
Anti-oxidant: Vitamin E
ECM Protector: liposome with Rutinyl Sulfate (Rutin) + L-HP (Hydroxyproline) + MAP(Magnesium Ascorbyl Phosphate – the only truly stable form of Vitamin C)
Efficacy of active ingredients*
Benefits provided by leading components include:
Benefits provided by ingredients typical to this age group include: