PRODUCTS Skincare Dermedics Dermedics Professional Skincare Gen'x Series

GEN'X Global Anti-Aging Cream #2 40~45+ 100ml

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Type: Cream


Global Anti-Aging Cream #2


Extraordinary Source of Youth

Free of paraben, colourants

*KLOTHO gene was discovered in 1997, in mice, to extend the lifespan when overexpressed, while it accelerates aging when its expression is disrupted. The name of this longevity gene comes from the Greek goddess Klotho. In Greek mythology, it was Klotho who controlled the lives and destinies of everyone. The Klotho gene codes for a transmembrane protein, the extra-cellular domain of which is shed and secreted. The secreted Klotho protein inhibits the phosphorylation of the IGF1 receptor which leads to the repression of the insulin / IGF-1 pathway. Therefore, Klotho activity results in an activation of **FOXOActivation of FOXO will induce anti-aging activity by stimulating detoxification and DNA-repair genes.

Telomere***The telomere is a region of non-coding DNA that is located at the ends of chromosomes (X- shaped).

****Glutathione peroxidase (GP) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.


General product view

YOUTH EXPERT™ Global Anti-Aging Cream #2 is a rich formulated, luxurious cream dedicated to prestigious skin therapies targeted on global rejuvenation – real results™. Cream is suitable for daily care for skin of all types of age 40~45+. .

Active ingredients*

Leading components 
GEN’X-17-GAA™ Complex: Orange Stem Cells + Baicalin (Telomere Protector) + Apitoxin (Bee Venom) + Crystal Tears™

Complementary components – typical to the age group
Re-densifying & Lifting: Lipodipeptide Tyrosyl-Arginyl
Anti-wrinkle Filler: 2x Hyaluronic Acid (cross-linked HA + HA 50 kDa)
Anti-oxidant: Vitamin E 
ECM Protector: liposome with Rutinyl Sulfate (Rutin) + L-HP (Hydroxyproline) + MAP(Magnesium Ascorbyl Phosphate – the only truly stable form of Vitamin C)

Efficacy of active ingredients*

Benefits provided by leading components include:

  • Re-activation of two youth proteins: KLOTHO* and FOXO**
  • Re-activation of cellular detoxification and the repair of RNA&DNA damages
  • Extension of  the length of telomeres’*** which are responsible for lifespan of cells
  • Protection of cells against high levels of free radicals and oxidative stress in the way of the expression of Cit-SAP - a protein with considerable homology to glutathione peroxidase**** (GP)
  • Re-activation of cellular activity (synthesis of collagen, elastin and fibrillin)
  • Increased microcirculation, thus accelerates skin oxygenation


Benefits provided by ingredients typical to this age group include:

  • Re-densification: increased synthesis of fibrillin and collagen in dermis
  • Skin looks younger: increased hydration, skin tone improved
  • Skin looks smoother: reduced roughness, wrinkle depth reduced
  • Lifting action: facial contours appear to be redrawn
Directions for use
  • Age group: mature skin of women aged 40~45+
  • Dull and sagging skin with wrinkles
  • Global rejuvenation on all levels of skin
  • All round anti-aging treatment to extend cell lifespan
  • Photo-protection against UV and free radicals (FR)
  • Daily skin care for skin of all types (night and/or day application)
Application area
Face, neck, décolletage, other (if desired).
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  • Luxurious therapies targeted on global rejuvenation
  • Anti-wrinkle therapies for skin aged 40~45+
  • Intensive re-densifying and lifting
  • Treatments targeted on visible effects – improvements of skin texture from first application!
For external use only. Keep out of the reach of children.
Contraindications: hypersensitivity to any component of the formulation.
Aqua, Butylene Glycol, Cyclopentasiloxane, Methylpropanediol, Caprylic/Capric Triglyceride, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Decyl Cocoate, Cetyl Alcohol, Propanediol, Glycerin, Hydrogenated Palm Kernel Glycerides, Hydrogenated Palm Glycerides, Myristyl Myristate, Triisostearin, Citrus Aurantium Dulcis (Orange) Callus Culture Extract, Ethylhexyl Stearate, Ethylhexylglycerin, Lecithin, Hydrolyzed Hyaluronic Acid, Polysorbate 60, Hydroxyethylcellulose, Pistacia Lentiscus (Mastic) Gum, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Sodium Hyaluronate Crosspolymer, Sodium Isostearate, Acetyl Dipeptide-1 Cetyl Ester, Bee Venom, Baicalin, Disodium Rutinyl Disulfate, Hydroxyproline, Sorbitol, Magnesium Ascorbyl Phosphate, Sorbitan Laurate, Bis-PEG/PPG-20/5 PEG/PPG-20/5 Dimethicone, Methoxy PEG/PPG-25/4 Dimethicone, Sorbitan Isostearate, PEG-7 Trimethylolpropane Coconut Ether, Gluconolactone, Xanthan Gum, Ascorbyl Palmitate, Polyisobutene, Ascorbic Acid, Tocopherol, Glyceryl Oleate, PEG-8, PPG-5-Ceteth-20, Glyceryl Stearate, Calcium Gluconate, Citric Acid, Parfum, Phenoxyethanol, Sodium Benzoate, Alcohol, Pentaerythrityl Tetra-di-tbutyl Hydroxyhydrocinnamate, Disodium EDTA.
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