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Further Education

42 Collagen Bodywave Technology: Training

42 Collagen BodyWave

Click here to read ABSTRACT CLINICAL/INSTRUMENTAL STUDYEvaluation of anti-wrinkle and anti-ageing efficacy of an aesthetic treatment for skin by 42 Collagen BodyWave. Study carried out at FARCODERM in co-operation with UNIVERSITY OF PAVIA

Skin ageing and Collagen
The Skin
The skin is composed by various elements including epidermis, dermis and fat cells.

The epidermis has a protective function. The dermis is the support for the epidermis and is responsible for its tone by two proteins, collagen to provide strength and elastin to provide elasticity. Fat cells are an important reserve of energy.

Collagen, a fibrous protein, is the primary support of the skin. It provides to the skin strength and suppleness, as well as an inherent ability to retain moisture, and makes up about 90% of dermal volume. 
Collagen is produced by the fibroblasts, essential cells of connective tissue. Over the years, the  physiological deposition of collagen decreases, with a consequent loss of tone of the skin. Above all after the age of 40-45 years, the ‘stratum corneum’ (horny layer) of the skin is thickening, while the dermis becomes gradually thinner. The reason why it occurs is indeed that collagen supporting action is gradually decreasing.
What result? A partial "collapse" of tissue, which looks less compact and tonic.
wrinkle A robust and compact dermis, thanks to collagen and elastic fibres means young skin and lack of wrinkles.

Wrinkles are caused by skin natural aging process. Cellular renewal becomes harder with ageing turning the skin thicker and
drier, the dermis less toned due to a decrease of collagen and elastin, ineffective cutaneous circulation with inadequate sprinkling of skin layers.
Starting Point: Given Technology
633nm light effects: Photo-bio-stimulation applied by 42 Collagen BodyWave

A large scientific evidence* demonstrates that a specific wavelength (633nm, normally contained into visible light spectrum) is able to stimulate the activity of fibroblasts, skin cells specialised in the production of collagen, a protein responsible for skin compactness.
633nm light prevents and mitigates ageing effects, contrasting tone loss on the whole body surface in a no-invasive way and without side effects.
In detail, the process is the following: 633nm light is absorbed by fibroblasts; inside each fibroblast there are some micro-organs, called mitochondrion, responsible for ATP (energetic reserve molecules) synthesis. This stimulation causes an increase of cellular activity and, as a consequence, a higher level of collagen production.

633 nm light

ATP production

Collagen Production

Finally, the absorption of 633 light by fibroblast generates an increase of collage production.

* Shin-ichiro Takezaki et al.: Light-emitting Diode Phototherapy at 630nm Increases Local Levels of Skin-homing T-cells
in Human Subjects, J Nippon Med Sch 2006; 73 (2)
R. Glen Calderhead, MSc, DrMedSci, FRSM: The Photobiology of LED Phototherapy.
Marshall Star Vol. 41/No. 16 NASA space technology shines new light on healing.
Harry T. Whelan, M.D. et al. : The NASA Light-Emitting Diode Medical Program – Progress in Space Flight and Terrestrial
G. Kesava Reddy et al. : Laser Photostimulation of collagen production in healing rabbit Achilles tendons.
R&D: New Technology Applied to Neon Tubes
633+ Collagen Activator to provide skin with new vitality
neontubes Technology innovation and cooperation with a multinational company of the field (manufacturer of low pressure light emitters) allowed Quadra Medical R&D to develop a new neon tube, able to totally cut the emission of UBA / UVB wavelength and to reduce infrared. By those new emitters, 633nm is increased of 500% with
respect to previous technology, with a maximum benefit for the effectiveness of collagen stimulation in a non-invasive way.

Irradiance values difference among new Collagen Activator 633+ tube lamp and other normal collagen tube lamp.
Collagen and skin aging

Collagen is the primary support structure of the skin.  It gives the skin strength and suppleness as well as an inherent ability to retain moisture, and makes up about 90% of dermal volume.

With ageing, collagen fibre components begin to weaken, become less pliable and tougher.  The result is the development of dry, wrinkled skin that has lost its inherent elasticity.42 Collagen BodyWave helps to arrest and reverse this condition!!!


Stimulating Collagen synthesis in aged skin was shown to reduce wrinkles and improve skin texture.  It is a new aesthetic possibility in the aging effect treatment.

42 Collagen BodyWave with 633nm red light

633nm is the most effective red light, very well known in the literature, that stimulates dermal cells and activates the cascade of events required to achieve reorganization and tightening of the skin supportive matrix. 633nm red light modulates the activity of the key cell in the dermis, the fibroblast, that produce collagen.



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